Personalized genomic massage, anyone?

Start with gene sequencing.

This is the genomic revolution today.

You don't know the sequencing.

like DNA sequencing or protein folding.

I got interested in gene sequencing.

And could Africa get that sequencing wrong?

Huge gene sequencing facilities the size of football fields.

And so we just heard about the DNA sequencing.

But that is changing rapidly with the aid of new genomic technology.

Guys, this would never have happened without whole genome sequencing.

DNA sequencing on your iPhone? There's an app for that.

The cost of sequencing the human genome is dropping precipitously.

The second question is, does the sequencing of the download matter?

It was the sequencing for the first time of the human genome.

And we're in the process of sequencing all that at the present time.

Moore's law, the old way of sequencing, and here's all the new stuff.

They're one of two companies that makes these massive whole genome sequencing tools.

Over 80 major diseases have been cracked at the genomic level, but this is quite extraordinary

Say again, Bishop. You've got it into auto refuel mode, and it's sequencing right?

So what I often like to say is that, from a genomic perspective, we are all Africans.

The genomic sequence now exists for the entire Pinot Noir organism, and they identified, once again, about 29,000 genes.

like cancer, we haven't been able to cure because we just don't understand how it works at the genomic level.

We were actually introduced because we both knew Linda Avey, one of the founders of the first online personal genomic companies.

We pump the fluid through one of these systems, and we press the button, and it's analyzed for the genomic character.

So, this may sound like genomic alchemy, but we can, by moving the software of DNA around, change things quite dramatically.

I mean, it's true of DNA sequencing it's true of brain scanning it's true of the World Wide Web.

The technologies got better, and now DNA sequencing is proceeding at a pace five times that of Moore's Law.

And that's what I've been doing for 20 years, using DNA sequencing, collecting samples from various places, including the human body, reading the DNA sequence and then using that DNA sequencing to tell us about the microbes that are in a particular place.

And so I urge you all to wake up and to tune in and to influence the genomic revolution that's happening all around you.

There's no molecular test, there's no sequencing of genes that was referred to yesterday, there's no fancy looking at the chromosomes.

And every kilogram of bush meat contained hundreds of thousands of novel viruses that have never been charted, the genomic sequences of which we don't know.

Any other living being which does not have your genomic sequence will be destroyed, as only you are destined to know the secret of immortality, Sou Ra!

So, it is the idea of sequencing all of the genes in the cancer, and giving us a new lexicon, a new dictionary to describe it.

And in both cases, we were able to use genetic sequencing to look at the polio viruses, and we could tell these viruses were not from these countries.

As you probably know, gene sequencing in a large part, because it's built on computers is falling in price at a kind of a Moore's Law like level.

So Jeanny and I took three of our most efficient strains and then performed gene amplification sequencing on them and matched our data with an online comprehensive database.

And as you're thinking about these two guys sequencing a human genome in 2000 and the Public Project sequencing the human genome in 2000, then you don't hear a lot, until you hear about an experiment last year in China, where they take skin cells from this mouse, put four chemicals on it, turn those skin cells into stem cells,

This is a project that had its inception 15 years ago when our team then we called the institute TlGR was involved in sequencing the first two genomes in history.

On any given plantation, 20 percent of the trees produce 80 percent of the crop, so Mars is looking at the genome, they're sequencing the genome of the cocoa plant.

But because each of your cells contains your entire gene code, each cell can be reprogrammed, if we don't stop stem cell research and if we don't stop genomic research, to express different body functions.

Fly away, cat. So, the last example I have time to show you today is a music sequencing and live performance tool that we've built recently, in which Siftables act as sounds

And what the DNA sequencing technologies are allowing people to do now is do detailed studies of, say, 100 patients who have Crohn's disease and 100 people who don't have Crohn's disease.

Synthetic DNA, the ability to synthesize DNA, has changed at sort of the same pace that DNA sequencing has over the last decade or two, and is getting very rapid and very cheap.

And as it continues, one of the things that's going to happen this year is we're going to discover the first 10,000 human genomes, because it's gotten cheap enough to do the gene sequencing.