Also, he's obnoxious.

Look at you, Lister... obnoxious, ruthless, singleminded, insensitive

in The Lady Vanishes when she says to me, You're the most obnoxious man...

You may just be loud or obnoxious, or some other way causing them to have the headache.

Thats the second brightest star, Procyon. That's it, benevolence at someone else's expense. You're always so outgoing and obnoxious

While continuous and I guess just another definition for the word discrete in the English language would be polite, or not obnoxious, or kind of subtle.

And I had no idea that I was one of those obnoxious people you occasionally see weaving in and out of traffic, because it was just that smooth.

So I started putting this in my slide decks, and I got even more obnoxious, and I went to my doctor, and I said, I'd like to actually get my bloodwork.

And what they do is, up until that time period when they can't strike, they become really obnoxious and awful, and they strike everything in sight it doesn't matter who or what.

If you find Sherlock Holmes annoying because his way of reasoning is obnoxious or showing off his super smartness, that's probably correct, but I think that Arthur Conan Doyle actually wanted to portray Sherlock Holmes as somebody who's not entirely likable.