We altered our ecological niche by creating civilization.

So, as you all know, species lived in particular ecological niches and particular environments, and the pressures of those environments selected which changes, through random mutation in species, were going to be preserved.

But it's going to have a big impact because we're going to have niche drugs.

You know, 20 years ago, some of the most amazing brands were built in the early days of cable, that met these new niche content demands from consumers.

It's particularly astonishing because each one of these organisms, each subsystem, each cell type, each gene, has evolved in its own unique environmental niche with its own unique history.

We're also looking at survival of the fittest, not in just competition terms in our modern context of destroy the other or beat them to the ground, but really to fit together and build niches and have growth that is good.

The women in this room and watching in L.A. and all around the world are not exceptions.

So let's see how they got from something that started over here which you shouldn't laugh because your first canvas might have looked like this and what happened after they got out of the building.

What's wrong?

Well, maybe I could drive.

RV, yeah?

Looking for a wheel for that coach.

Dad's car looks like that one.

Y'all better have some real cars around here.

A4 it should be local, run by communities, or niche, for some smaller groups like business but then it's not free it's very expensive.

Where's that car?

He came by car instead of by train.

Where are the rescuers?

I'm really bad at parallel parking.

Is this your car?

What kind of car was it?

Lock him to the wheel of that car.

Well, we need a car.

Whichever one you are.

Nice ride.

A nice car.

That's my kind of ride.

What's the difference here, the wheelchair with no lights and the wheelchair with lights?

So here's an example of a business model canvas from a life sciences company that was going to provide E. coli cell lines for simplified downstream processing.

My car's in the... it's in the garage.

If you go at 52 km per hour when the speed limit is 50, you lose points

What kind of piece of shit car is this?

A couple of cars went by out there and that's about it.

It turns out that for some number of categories, we have got an EP which is above 50 . So, this means of transportation like motorbike, bicycle, bus, car, and so on.

Car 12. Car 12.

Anyway take care of yourself. I'm going. I'm going.

You want to keep it?

I'll lock you into the wheel of that car.

They said stay near the car.

Do we have a car?

You don't have a car?

We need our cars washed.

Don't shake the car!

Stay in the car, out of the wind.

Gray sedan, right?