So these articles were saying, you know, Skeletal metastasis to skeletal muscle is very rare.

You see the skeletal structure of it.

And the other really interesting thing is that when skeletal muscle there's been several reports that when skeletal muscle is injured, that's what correlates with metastases going to skeletal muscle.

Some of my hypotheses are that when you first think about skeletal muscle, there's a lot of blood vessels going to skeletal muscle.

So, is it possible that the tumor cells are going to the skeletal muscle tissue, but once in contact inside the skeletal muscle tissue,

Hey, it seems like cancer doesn't really go to skeletal muscle.

Is it possible that skeletal muscle doesn't express this type of molecules?

Some articles even went as far as to say that skeletal muscle tissue is resistant to cancer, and furthermore, not only to cancer, but of metastases going to skeletal muscle.

So the fact that not only did cancer not seem to originate in skeletal muscles, but cancer didn't seem to go to skeletal muscle there seemed to be something here.

The fetus' continual movement in the womb is necessary for muscular and skeletal growth.

And, furthermore, when skeletal muscle is injured, that's what causes chemokines these signals saying,

MyoD acts upon these tumor cells and causes them to become skeletal muscle cells?

These bones are like a skeleton, so this whole area is sometimes called skeletal animation.

Deeper than that pitiful, twisted lump of flesh deeper even than that misshapen skeletal mask.

I mean, there are so many possibilities for why tumors don't go to skeletal muscle.

I'm going to start with the skeletal structure, and I can add a few internal organs.

I really wanted to find a dissertation project that would expand our knowledge of skeletal function.

And skeletal muscle constitutes 50 percent of our body, or over 50 percent of our body.

Why do they do that?... also this sort of skeletal structure reminds me of bones so

The skeletal remains from that period have shown that they were grinding grain morning, noon and night.

So, basically, ideally then our muscular skeletal body, our chemicals and hormones are working in our body.

We can replace the underlying skeletal structure, but we're still not good at replacing the facial skin.

But then again, this fact that the metastases didn't go to skeletal muscle made that seem unlikely.

We use skeletal muscles so much. It's the one portion of our body our heart's always beating.

Meaning that there were these pinpoint tumors in skeletal muscle, but only .16 percent of actual metastases suggesting that maybe skeletal muscle is able to control the angiogenesis, is able to control the tumors recruiting these blood vessels.

Now, one thing that kind of ties the resistance of skeletal muscle to cancer to the cancer as a repair response gone out of control in the body is that skeletal muscle has a factor in it called MyoD.

Therefore, when a tumor comes into skeletal muscle tissue, it can't get a blood supply, and can't grow.

Well, maybe there's some obvious explanation why skeletal muscle doesn't get cancer at least not that I know of.

And one article that really stood out to me when I was just reading about this, trying to figure out why cancer doesn't go to skeletal muscle, was that it had reported 16 percent of micro metastases to skeletal muscle upon autopsy.

But it struck me that I'd never heard of cancer of the heart, or cancer of any skeletal muscle for that matter.

At first the first thing I did was I emailed some professors who specialized in skeletal muscle physiology, and pretty much said,

Maybe tumor cells are being disguised as skeletal muscle cells, and this is why it seems as if it is so rare.

Two elements that worked for me here are the first is 90 percent, I learned, of head and neck pain is through muscular skeletal imbalance.

The skeletal tree limbs submerged in Lake Volta often catch the fishing nets, and weary, frightened children are thrown into the water to untether the lines.

The skeletal support comes from an interaction between a pressurized fluid and a surrounding wall of tissue that's held in tension and reinforced with fibrous proteins.

So this compound, MyoD, has been tested on a lot of different cell types and been shown to actually convert this variety of cell types into skeletal muscle cells.

And so I thought, Here's a problem that just cries out for a skeletal system not one like this one, but one like this one because, functionally, a skeleton is any system that supports tissue and transmits forces.

I'm an archeological geneticist at the Center for Evolutionary Medicine at the University of Zurich, and I study the origins and evolution of human health and disease by conducting genetic research on the skeletal and mummified remains of ancient humans.

So this suggests that maybe if there is an anti angiogenic factor in skeletal muscle or perhaps even more, an angiogenic routing factor, so it can actually direct where the blood vessels grow this could be a potential future therapy for cancer.

So first of all I thought, you know, Wouldn't it be favorable to cancer getting to skeletal muscle? And as well, cancer tumors require a process called angiogenesis, which is really, the tumor recruits the blood vessels to itself to supply itself with nutrients so it can grow.