Chronic viral ulcerative lesion.

It's a... a cystic mass.

It's just a lesion formed inside.

And you had a big sign promoting Shinerama, which is Students Fighting Cystic Fibrosis,

Actually, sometimes the parents argue about whether these children should have the lesion removed.

And other children in curiosity come up and poke the lesion, because a natural curiosity.

Either one would kill you in only one of them will you find a major lesion.

Either one would kill you, and in only one of them will you find a major lesion.

One that has just happened in the last few months is the successful approval of a drug for cystic fibrosis.

And you had a big sign promoting Shinerama, which is Students Fighting Cystic Fibrosis, a charity I've worked with for years

Okay, when you hear the click, this is when the energy starts to emit and you see a little lesion form inside the phantom.

Although their brains continue to produce those storms and code for movements, they cannot cross a barrier that was created by a lesion on the spinal cord.

Cystic fibrosis had its molecular cause discovered in 1989 by my group working with another group in Toronto, discovering what the mutation was in a particular gene on chromosome 7.

The bad news is, this drug doesn't actually treat all cases of cystic fibrosis, and it won't work for Danny, and we're still waiting for that next generation to help him.

Compare those two pictures, and now as a radiologist, you can essentially fly through your patient's colon and, augmenting that with artificial intelligence, identify potentially, as you see here, a lesion.

Cystic fibrosis is an example of a disease where you just have a bad ingredient and you have a disease, and we can actually make a direct correspondence between the ingredient and the disease.

There is a unique opportunity now with focused ultrasound guided by MR, because we can actually think about prostate lumpectomy treating just the focal lesion and not removing the whole gland, and by that, avoiding all the issues with potency and incontinence.

larger scale brainstorms that contain the desire to move again, bypass the lesion using computational microengineering and send it to a new body, a whole body called an exoskeleton, a whole robotic suit that will become the new body of these patients.

That's Danny Bessette, 23 years later, because this is the year, and it's also the year where Danny got married, where we have, for the first time, the approval by the FDA of a drug that precisely targets the defect in cystic fibrosis based upon all this molecular understanding.